Acta Anaesthesiologica Taiwanica
Volume 47, Issue 4 , Pages 167-172 , December 2009

Optimizing Epidural Fentanyl Loading Dose for Early Labor Pain

  • Feng-Fang Tsai

      Affiliations

    • Department of Anesthesiology, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan, R.O.C.
    • ,
  • Gong-Jhe Wu

      Affiliations

    • Department of Anesthesiology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan, R.O.C.
    • ,
  • Chen-Jung Lin

      Affiliations

    • Department of Anesthesiology, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan, R.O.C.
    • ,
  • Chi-Hsiang Huang

      Affiliations

    • Department of Anesthesiology, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan, R.O.C.
    • ,
  • Shiou-Sheng Chen

      Affiliations

    • Department of Urology, School of Medicine, National Yang-Ming University, Taipei, Taiwan, R.O.C.
    • ,
  • Li-Kuei Chen

      Affiliations

    • Department of Anesthesiology, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan, R.O.C.
    • Corresponding Author InformationCorresponding author. Department of Anesthesiology, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei, Taiwan, R.O.C.

Received 19 May 2008 ,Revised 3 July 2009 ,Accepted 8 July 2009.

References 

  1. Morgan B , Bulpitt CJ , Clifton P , Lewis PJ . Effectiveness of pain relief in labour: survey of 1000 mothers . Br Med J (Clin Res Ed) . 1982;285:689–690
  2. Philipsen T , Jensen NH . Epidural block or parenteral pethidine as analgesic in labour. A randomized study concerning progress in labor and instrumental deliveries . Eur J Obstet Gynecol Reprod Biol . 1989;30:27–33
  3. Justins DM , Francis D , Houlton PG , Reynolds F . A controlled trial of extradural fentanyl in labour . Br J Anaesth . 1982;54:409–414
  4. Skerman JH , Thompson BA , Goldstein MT , Jacobs MA , Gupta A , Blass NH . Combined continuous epidural fentanyl and bupivacaine in labor: a randomized study . Anesthesiology . 1985;63:A450
  5. Chestnut DH , Owen CL , Bates JN , Ostman LG , Choi WW , Geiger MW . Continuous infusion epidural analgesia during labor: a randomized, double-blind comparison of 0.0625% bupivacaine/0.0002% fentanyl versus 0.125% bupivacaine . Anesthesiology . 1988;68:754–759
  6. Cohen SE , Tan S , Albright GA , Halpern J . Epidural fentanyl/ bupivacaine mixtures for obstetric analgesia . Anesthesiology . 1987;67:403–407
  7. Elliott RD . Continuous infusion epidural analgesia for obstetrics: bupivacaine versus bupuvacaine-fentanyl mixture . Can J Anaesth . 1991;38:303–310
  8. Bromage PR . Epidural Anesthesia . Philadelphia: Saunders; 1978;
  9. Vercauteren M , Meert TF . Isobolographic analysis of the interaction between epidural sufentanil and bupivacaine in rats . Pharmacol Biochem Behav . 1997;58:237–242
  10. Lyons G , Columb M , Hawthorne L , Dresner M . Extradural pain relief in labour: bupivacaine sparing by extradural fentanyl is dose dependent . Br J Anaesth . 1997;78:493–496
  11. Cherng CH , Wong CS , Ho ST . Epidural fentanyl speeds the onset of sensory block during epidural lidocaine anesthesia . Reg Anesth Pain Med . 2001;26:523–526
  12. Liu SS , Gerancher JC , Bainton BG , Kopacz DJ , Carpenter RL . The effects of electrical stimulation at different frequencies on perception and pain in human volunteers: epidural versus intravenous administration of fentanyl . Anesth Analg . 1996;82:98–102
  13. Coda BA , Brown MC , Risler L , Syrjala K , Shen DD . Equivalent analgesia and side effects during epidural and pharmacokinetically tailored intravenous infusion with matching plasma alfentanil concentration . Anesthesiology . 1999;90:98–108
  14. Singh H , Yang J , Thornton K , Giesecke AH . Intrathecal fentanyl prolongs sensory bupivacaine spinal block . Can J Anaesth . 1995;42:987–991
  15. Ginosar Y , Riley ET , Angst MS . The site of action of epidural fentanyl in humans: the difference between infusion and bolus administration . Anesth Analg . 2003;97:1428–1438
  16. Eichenberger U , Giani C , Petersen-Felix S , Graven-Nielsen T , Arendt-Nielsen L , Curatolo M . Lumbar epidural fentanyl: segmental spread and effect on temporal summation and muscle pain . Br J Anaesth . 2003;90:467–473
  17. Chestnut DH , Laszewski LJ , Pollack KL , Bates JN , Manago NK , Choi WW . Continuous epidural infusion of 0.0625% bupivacaine-0.0002% fentanyl during the second stage of labor . Anesthesiology . 1990;72:613–618
  18. Vertommen JD, Vandermeulen E, Van AH, Vaes L, Soetens M, Steenberge AV, et al  The effects of the addition of sufentanil to 0.125% bupivacaine on the quality of analgesia during labor and on the incidence of instrumental deliveries . Anesthesiology . 1991;74:809–814
  19. Chaney MA . Side effects of intrathecal and epidural opioids . Can J Anaesth . 1995;42:891–903

PII: S1875-4597(09)60050-3

doi: 10.1016/S1875-4597(09)60050-3

Acta Anaesthesiologica Taiwanica
Volume 47, Issue 4 , Pages 167-172 , December 2009

Article Tools